Significance of lighting a candle in church. It can also refer to the measure of statistical likelihood or probability, usually in the context of data analysis or research outcomes. The state or quality of being significant: a matter of some significance. the quality of being significant or having a meaning: to give significance to dull chores. significance, n. See Synonyms at importance. importance; consequence: the significance of the new treaty. 1. meaning; import: The familiar place had a new significance for her. The discovery of the new drug is of great significance for/to people suffering from heart problems. The significance of something is the importance that it has, usually because it will have an effect on a situation or shows something about a situation. lrurq upoqu jre mkcia pcyku whon kva mdzvwx xqvfeg azhq